Listen to today’s podcast: https://www.youtube.com/channel/UC-nqwUyvLDEvs7bV985k-gQ
Stock Market Daily Podcast — January 21, 2026
Today’s podcast episode was created from the following stories:
New York Stock Exchange building venue for 24/7 tokenized stock and ETF exchange — will leverage blockchain to work around the clock in a bid to modernize trading
The NYSE is building a new venue for 24/7, instantly settled trading of tokenized stocks and ETFs, integrating its Pillar matching engine with blockchain infrastructure. The platform aims to preserve shareholder rights while enabling after-hours cash management via tokenized deposits in partnership with Citi and BNY, with stablecoins facilitating settlement. ICE is in discussions with the SEC, signaling a push to modernize market plumbing beyond traditional trading hours.
NYSE’s tokenized stocks create more questions for crypto’s relevance
NYSE’s tokenization plan is reportedly built on private, permissioned blockchains, underscoring a growing split between centralized finance rails and open, public crypto networks like Ethereum or Solana. The move spotlights regulatory uncertainty (including elements of the CLARITY Act) and a broader industry trend toward control and monetization by incumbents, even as some tokenized equities and fintech efforts remain on public chains. The debate centers on who controls settlement layers, the role of stablecoins, and how much decentralization is sacrificed as institutional adoption accelerates.
GSK acquires RAPT Therapeutics for $2.2bn
GSK is buying RAPT Therapeutics for up to $2.2 billion, paying a significant premium to secure ozureprubart, a long-acting anti-IgE candidate for food allergy with convenient once-quarterly dosing now in Phase IIb. The deal bolsters GSK’s immunology pipeline and positions the company ahead of looming patent expiries, complementing broader investments in AI-driven R&D and earlier strategic partnerships. Investors see the move as a targeted bet on a potential best-in-class asset that could reshape food allergy treatment if approved.
